Free shipping over $7560-day money-back guaranteeThird-party testedGMP CertifiedVegan & Non-GMOMade in USAFree shipping over $7560-day money-back guaranteeThird-party testedGMP CertifiedVegan & Non-GMOMade in USA
CoreBioVital NAD+ Synergy™
Mitochondrial Performance · Longevity

Rebuild the cellular energy that built your edge.

60-day money-back guarantee
5.0 · Early adopter reviews

Verified via direct customer feedback · Third-party review integration coming Q3 2026

A flagship NAD+ system engineered to restore mitochondrial output, slow biological wear and protect the engine behind every other goal you have.

After 30, NAD+ levels decline up to 50%. With them goes mental sharpness, recovery, and the quiet sense of vitality that used to feel automatic. NAD+ Synergy™ is built to rebuild that foundation — at the cellular level, every single day.

$57.80$68.00
60 capsules · 30-day supply · billed monthly
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NAD+ Synergy
$57.80
What this formula supports

Six outcomes engineered into a single capsule.

Restores NAD+ levels

Replenishes the coenzyme central to mitochondrial energy and DNA repair.

Sustained cellular energy

Stable ATP output without stimulants, crashes or dependency.

Healthy aging pathways

Activates sirtuins and antioxidant defense that protect long-term biology.

Mental clarity & focus

Supports neuronal energy, working memory and end-of-day cognitive load.

Cardiovascular resilience

Polyphenols and CoQ10 support vascular and heart muscle function.

Visible vitality

The downstream signal of better mitochondria — skin, eyes, posture, presence.

How it works

How NAD+ Synergy works inside the cell.

Three layered actions: replenish the precursor, activate the longevity switches, protect the mitochondria you already have.

  1. 01
    Replenish NAD+

    Nicotinamide Riboside crosses into the cell and converts directly into NAD+, the master coenzyme for energy metabolism.

  2. 02
    Activate sirtuins

    Trans-Resveratrol and Quercetin signal sirtuin pathways that regulate DNA repair, inflammation and metabolic health.

  3. 03
    Protect mitochondria

    PQQ stimulates new mitochondrial growth while CoQ10 shields the membrane from oxidative damage.

Inside the formula

Dosed transparently. No proprietary blends.

NAD+ Synergy is engineered as a closed-loop system: precursor → activator → protector → builder. Removing any one component breaks the chain.

Nicotinamide Riboside
300 mg

Direct NAD+ precursor.

Why it matters

Clinically shown to elevate blood NAD+ by 40–90% at this dose. The most bioavailable, best-studied precursor available. [View study ↗]

Synergy

Pairs with Resveratrol to activate sirtuin pathways NAD+ alone cannot fully turn on.

Trans-Resveratrol
250 mg

Polyphenol longevity activator.

Why it matters

Activates SIRT1, the gene linked to lifespan extension in mammalian studies. Trans- form for true bioactivity. [View study ↗]

Synergy

NAD+ is the fuel; resveratrol is the ignition. Each is limited without the other.

Quercetin
200 mg

Senolytic bioflavonoid.

Why it matters

Helps clear senescent ('zombie') cells that drive low-grade inflammation and accelerated aging.

Synergy

Amplifies resveratrol absorption and complements NR's longevity signaling.

PQQ
20 mg

Mitochondrial biogenesis cofactor.

Why it matters

One of the only known compounds shown to trigger growth of new mitochondria — not just protect existing ones. [View study ↗]

Synergy

Builds the cellular machinery that NR and CoQ10 then fuel and protect.

CoQ10 (Ubiquinone)
100 mg

Mitochondrial coenzyme.

Why it matters

Sits inside the electron transport chain — the final step of ATP production. Declines steeply after 35.

Synergy

Protects the mitochondrial membrane while PQQ builds new ones.

Black Pepper Extract
5 mg

Bioavailability enhancer.

Why it matters

Increases absorption of resveratrol and quercetin by up to 20× via liver enzyme modulation.

Synergy

Ensures the actives actually reach systemic circulation, not the toilet.

Protocol

How to use it well.

Timing
Morning, with your first meal.
Routine

Stack with daylight, protein and 10 minutes of movement to maximize mitochondrial signal.

Consistency

Run continuously for 8–12 weeks. NAD+ restoration is cumulative — not acute.

Quality & sourcing

Built to a standard you can audit.

Made in USA

Formulated and manufactured in FDA-registered facilities.

GMP Certified

Pharmaceutical-grade quality control on every batch.

Third-Party Tested

Independently verified for purity, potency and contaminants.

Request Certificate of Analysis →
Non-GMO

No genetically modified ingredients, ever.

Vegan Capsules

Plant-based capsules. No gelatin, no animal byproducts.

No Fillers

No magnesium stearate, silica, dyes, or proprietary blends.

What men are saying

Feedback from operators, athletes, founders.

"Six weeks in, the 3pm wall is gone. Not stimulated — just steady. First supplement I've kept on auto-ship."

Marcus T. · Austin TX · 41
Verified buyer
Purchased: NAD+ Synergy · March 2026

"Recovery between long shifts is measurably faster. My HRV on Whoop is the highest in two years."

Daniel R. · Chicago IL · 47
Verified buyer
Purchased: NAD+ Synergy · March 2026

"Finally a brand that doses what the literature actually says. I tell my doctor friends to read the label first."

Henrik B. · New York NY · 52
Verified buyer
Purchased: NAD+ Synergy · March 2026
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Common questions

Everything you need to decide.

How is this different from a standalone NR or NMN supplement?+

NAD+ alone is fuel without ignition. NAD+ Synergy combines the precursor with sirtuin activators (resveratrol, quercetin) and mitochondrial protectors (PQQ, CoQ10) so the system actually works end-to-end.

When will I notice changes?+

Subtle clarity and steadier energy typically appear by week 2–4. The deeper biological effects (recovery, sleep quality, body composition signals) emerge over 8–12 weeks of consistent use.

Is it safe long-term?+

Yes. Every compound is at a dose used in published human studies, third-party tested, and free of stimulants or hormones.

Can I take it with my prescription medication?+

NAD+ Synergy is well-tolerated, but if you're on blood thinners or have a medical condition, share the label with your physician first.

Why capsules instead of powder or IV?+

Capsules deliver a stable, daily, measurable dose. IV NAD+ is acute and expensive; daily oral precursors are what move the long-term baseline.

Cellular Longevity Formula

Rebuild the cellular energy that built your edge.

One bottle. 30 days. Engineered to move a single specific outcome — measurably.