NAD+ Synergy™
NAD+, Quercetin and Japanese Knotweed (98% Resveratrol) — three ingredients, dosed transparently.
A focused three-ingredient formula: 500 mg of NAD+ paired with 250 mg of quercetin (Sophora japonica) and 150 mg of Japanese Knotweed extract standardized to 98% resveratrol — designed to support healthy cellular aging and antioxidant defense.
- Cellular Coenzyme500 mgNAD+ (Nicotinamide Adenine Dinucleotide)
- Antioxidant Bioflavonoid250 mgQuercetin Dihydrate (Sophora japonica)
- Resveratrol Source150 mgJapanese Knotweed (98% Resveratrol)
Three actives per 2-capsule serving. Designed to support healthy cellular aging and antioxidant defense.
If you're not completely satisfied, simply contact us within 60 days for a full refund.
- 30-Day Supply
- 2 Capsules Daily
- Ships From USA

Six outcomes engineered into a single capsule.
Supports stable, all-day cellular ATP output without stimulants.
Supports the longevity pathways central to healthy cellular aging.
Delivers 500 mg of NAD+, the coenzyme central to energy metabolism.
Quercetin and resveratrol contribute plant polyphenol antioxidant activity.
Three ingredients. One focused formula.
NAD+ Synergy pairs NAD+ itself with two of the most studied plant polyphenols — quercetin and resveratrol.
- 01Deliver NAD+
Each serving provides 500 mg of NAD+ (Nicotinamide Adenine Dinucleotide), the coenzyme central to cellular energy metabolism.
- 02Add polyphenol antioxidants
250 mg of quercetin dihydrate (from Sophora japonica) contributes bioflavonoid antioxidant activity.
- 03Anchor with resveratrol
150 mg of Japanese Knotweed (Polygonum cuspidatum) standardized to 98% resveratrol — the polyphenol most associated with sirtuin research.

Dosed transparently. No proprietary blends.
A short, transparent label: NAD+, quercetin and resveratrol at meaningful doses. Other ingredients: HPMC (vegetable capsule), MCC, brown rice flour, olive oil, silicon dioxide, magnesium stearate.
Cellular coenzyme central to energy metabolism.
NAD+ is the coenzyme mitochondria use to convert nutrients into ATP and that sirtuins use in cellular repair pathways. Tissue NAD+ declines with age.
Bioflavonoid from Sophora japonica flower bud.
Quercetin is one of the most studied dietary flavonoids and contributes antioxidant activity. [View study ↗]
Traditionally paired with resveratrol in polyphenol research.
Standardized resveratrol source from Polygonum cuspidatum root.
Japanese Knotweed is the highest-yield natural source of trans-resveratrol used in longevity research. [View study ↗]
Works alongside quercetin as a plant polyphenol pair.
Built Around NAD+, Quercetin and Resveratrol
NAD+ is one of the most studied molecules in healthy aging research. NAD+ Synergy delivers 500 mg of NAD+ directly, paired with 250 mg of quercetin (from Sophora japonica) and 150 mg of Japanese Knotweed extract standardized to 98% resveratrol — a focused three-ingredient formula for cellular support and antioxidant defense.
A focused three-ingredient formula, transparently dosed.
Built for people who refuse to slow down.
Sustained drive across long work cycles.
Mental clarity for high-stakes execution.
Cellular fuel for training and recovery.
Peak output without the afternoon crash.
Foundational support for healthy aging.
A multi-pathway approach to cellular biology.
How to use it well.
Stack with daylight, protein and 10 minutes of movement to maximize mitochondrial signal.
Run continuously for 8–12 weeks. Effects of NAD+ and plant polyphenols are cumulative.
Built to a standard you can audit.
Formulated and manufactured in FDA-registered facilities.
Pharmaceutical-grade quality control on every batch.
Independently verified for purity, potency and contaminants.
Request Certificate of Analysis →No genetically modified ingredients, ever.
Plant-based capsules. No gelatin, no animal byproducts.
Every ingredient and dose disclosed on the Supplement Facts panel. See each product page for other ingredients.
Feedback from operators, athletes, founders.
"Six weeks in, the 3pm wall is gone. Not stimulated — just steady. First supplement I've kept on auto-ship."
"Recovery between long shifts is measurably faster. My HRV on Whoop is the highest in two years."
"Finally a brand that doses what the literature actually says. I tell my doctor friends to read the label first."
Everything you need to decide.
What's actually in this formula?+
Three actives per 2-capsule serving: 500 mg NAD+, 250 mg quercetin dihydrate (from Sophora japonica flower bud) and 150 mg Japanese Knotweed extract standardized to 98% resveratrol. Other ingredients: HPMC vegetable capsule, MCC, brown rice flour, olive oil, silicon dioxide, magnesium stearate.
Does it contain NR, NMN, CoQ10 or PQQ?+
No. NAD+ Synergy uses NAD+ directly, quercetin and resveratrol. It does not contain nicotinamide riboside, NMN, CoQ10, PQQ or a BioPerine® bioavailability enhancer.
When will I notice changes?+
Effects of NAD+ and plant polyphenols are typically cumulative. Most users evaluate the formula on an 8–12 week horizon of consistent use.
Is it safe long-term?+
The formula is intended for daily use and is third-party tested. If you take prescription medication, are pregnant or nursing, or have a medical condition, consult a healthcare professional first — resveratrol and quercetin can interact with certain medications.
How do I take it?+
2 capsules daily with 6 fl oz (177 ml) of water, or as directed by a healthcare professional.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any new dietary supplement.
NAD+ Synergy™
One bottle. 30 days. Engineered to move a single specific outcome — measurably.