Focus is a cholinergic system
Sustained attention depends on acetylcholine availability in the prefrontal cortex. Most modern diets do not provide enough choline to support several hours of demanding cognitive work.
Alpha GPC + Citicoline
Two complementary choline donors. Alpha GPC raises acetylcholine quickly; Citicoline supports the structural phospholipids of neurons (phosphatidylcholine) for longer-term integrity.
Lion's Mane (Hericium erinaceus)
Contains hericenones that cross the blood-brain barrier and stimulate Nerve Growth Factor (NGF) synthesis. Mori et al. (2009) showed cognitive improvement in older adults after 16 weeks of supplementation.
L-Tyrosine + Rhodiola Rosea
Tyrosine is the precursor to dopamine and norepinephrine — depleted under cognitive load. Rhodiola is an adaptogen that protects mental performance in stress and sleep-deprivation studies.
L-Theanine
Raises alpha-wave activity and smooths the edge of any concurrent caffeine — sustained calm focus instead of jittery acceleration.
- 01Mori K. et al., Phytotherapy Research, 2009.
- 02Parker A. et al., J Int Soc Sports Nutr, 2011 (Citicoline).
- 03Olsson E. et al., Planta Medica, 2009 (Rhodiola).
Editorial note: this article is provided for educational purposes and is not medical advice. Discuss supplementation with a qualified clinician, especially if you take prescription medication or have a medical condition.
